Bupropion works a bit differently than these other antidepressants - rather than regulating the mood-affecting chemical serotonin, bupropion affects levels of norepinephrine and dopamine, two other brain chemicals that impact stress, motivation, and pleasure. Bupropion is a norepinephrine-dopamine reputable inhibitor (NDRI), while others include monoamine oxidase inhibitors (MAOIs) or selective serotonin reuptake inhibitors (SSRIs), such as Celexa (brand name: citalopram). To give you some background, antidepressants are often grouped into categories based on the chemicals they influence in the brain. Talking with your health care provider about your symptoms and your dosage may help you continue to reap the benefits of treatment while alleviating the more unpleasant effects. In most cases, though, starting with a low dose and gradually increasing over a period of time can allow you to adjust, making the effects mild enough to manage. However, it’s also been known to cause restlessness, anxiety, insomnia, agitation, excitement, and shaking. Many patients report a similar experience on the medication of reduced depression symptoms and increased libido. Wellbutrin (generic name: bupropion) is a treatment for major depressive disorder, seasonal affective disorder (SAD), and smoking cessation ( quitting smoking). While it’s great that your new medication has improved your mood and restored your sex life, feeling like your body is racing a mile a minute can be a frustrating side effect.
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